Antonio Conte's men suffered a 1-0 loss at West Ham this weekend and the result left them 14 points behind Premier League leaders Manchester City.
Now, Azpilicueta wants his side to show their fight and put in a ‘strong’ performance at the John Smith's Stadium.
'Big teams, after a defeat, we have to answer in a strong way,' Azpilicueta told the club's website.
'We know it is a tough place. We have the character and hopefully we can get the three points.
'We are in December and we cannot think more than this.
'We have a tough game against Huddersfield, we will try to get the three points on the road and get back to winning ways and keep going, keep pushing.'