Speaking to 'Premier League Daily', Wise said: "At some stage if he doesn't get regular football that will be something of a consideration for him further down the line.
"There are some quality players that they have brought in. There is Lukaku that he has got to try and get himself in front of - I am not sure he will," he continued. "Although Lukaku has not been performing fantastically well. Sanchez is another one that Mourinho has brought in. It's about where they are going to fit Rashford in and what position.
"At times he has mostly played wide and that is not really his main position but I think he will accept that position because he wants to play," Wise concluded.
Rashford will be hoping to force his way into England's squad for the World Cup, and will be eager to take any chance he is given, the first of which could be against Chelsea this weekend.