City are yet to lose in 17 Premier Lague games so far this season, though Rose is confident that Spurs can put an end to that run at the weekend.
The north Londoners have previous, with a 2-0 win last season ending City's 100% start to the campaign and putting Pep Guardiola's side into a downward spiral.
Spurs have been in good form against City of late, winning three and drawing one of the last five meetings between the twp sides and England international Rose is backing them to continue that streak.
'We'll go there and relish it,' Rose said. 'At the minute, they do look very frightening - scoring goals, they've kept a clean sheet last night. But we've done alright there in the past couple of seasons and that should give us some confidence at the weekend.
'We were the first ones to beat City last season, we disrupted Chelsea's unbeaten run. It's a challenge we all look forward to.
'It's a challenge the manager looks forward to. In these games, he knows he's going to get 100% from everyone. There's going to be a lot of eyes watching us this weekend.
'We haven't done so well away from home against the top teams this season so we hope to go there with some confidence and keep pushing on after three wins that we've had over the last week.'
Whilst history may be on Spurs' side, it is worth noting that Mauricio Pochettino's men have managed just one win from their last 17 trips to fellow top six sides.
'There is pressure on us from ourselves and the manager - he demands the best from us in every game so I wouldn't like to think any of us think there's no pressure on us,' Rose added.
'We know our standards and whenever we slip from those standards the manager lets us know.
'So I say there is pressure on us and we look forward to going there and being the first team to beat them this season, as we did last season.'